Acquired reactive perforating collagenosis successfully treated with narrow-band ultraviolet B.

© 2009 The Authors. doi: 10.2340/00015555-0685 Journal Compilation © 2009 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Acquired reactive perforating collagenosis (ARPC) is associated with diabetes mellitus and/or chronic renal failure. The disease lesions consist of many dome-shaped nodules, which have a central umbilication containing firm keratotic plugs. Histologically, transepidermal elimination of degenerated collagen fibres and marked neutrophil infiltrations are characteristic features. ARPC is usually refractory to treatment; however, there have been reports of ARPC treated with phototherapy. In the present case, we treated the patient with narrow-band ultraviolet B (NBUVB) phototherapy. After 20 exposures (total 18.96 J/cm2), all of the nodules had completely disappeared.